Influence of Proteins Adsorbed on Erythrocyte Memb ranes on Bioimpedance Spectroscopy Parameters of Red Blood Cells Suspensions

Malakhov Maksim Viktorovich, Melnikov Vladimir Alekseyevich, Vikulov Aleksandr Demyanovich

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The influence of the proteins adsorbed on the red blood cells membranes on the bioimpedance spectroscopy (BIS) parameters of the erythrocyte suspensions was studied. The suspensions of the erythrocytes treated and untreated with trypsin were estimated. The BIS parameters: extracellular (Re) and intracellular (Ri) fluid resistance, characteristic frequency (Fchar), cell membranes capacitance (Cm) and Alpha parameter of the suspensions were measured on the BIA analyzer ABC-01 «Medass». It was found that Ri and Cm of the suspensions of treated erythrocyte were lower than that of the untreated one. So the proteins adsorbed on the membrane surface influence the BIS parameters.

Keywords: Erythrocytes, bioimpedance spectroscopy, adsorbed membrane proteins

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Issue: 5, 2011

Series of issue: Issue 5

Rubric: Biology

Pages: 66 — 68

Downloads: 1127