Synthesis of azomethines 8-benzodioxane 4-amino-1-phenyl-2,3-dimethylpyrazolone-5

Tlegenov R. T.

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At the condensation 4-amino-1-phenyl-2,3-dimethylpyrazolone-5 with appropriate 8-benzodioxane aldehydes were synthesized earlier not known azomethines. The structure is confirmed by spectral methods. Is shown, what azomethine have none antitubercular of activity against штамма H37Rv in concentration 12.5 (јg/ml) also do not show activity against anti-HIV CEM-SS at concentration 5,00 х 10-5 in vitro. Among synthesized azomethines I-III the amplification of antibacterial activity is revealed at introduction in structure nitro of group

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Issue: 6, 2007

Series of issue: Science

Pages: 30 — 33

Downloads: 1113